Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
Which of the following statements is not true for cancer cells in relation to mutations?
Mutations in proto-oncogenes accelerate the cell cycle.
Mutations destroy telomerase inhibitor.
Mutations inactivate the cell control.
Mutations inhibit production of telomerase.
To solve this problem, we need to analyze each statement regarding cancer cells and mutations:Option 1: Mutations in proto-oncogenes accelerate the cell cycle. - Proto-oncogenes are normal genes that, when mutated, become oncogenes and can lead to uncontrolled cell division. - This statement is true because mutations in proto-oncogenes can indeed accelerate the cell cycle.Option 2: Mutations destroy telomerase inhibitor. - Telomerase inhibitors are molecules that can inhibit the activity of telomerase, an enzyme that maintains telomere length. - Mutations that destroy these inhibitors can lead to increased telomerase activity, which is often seen in cancer cells. - This statement is true as it describes a mechanism by which cancer cells maintain their telomeres.Option 3: Mutations inactivate the cell control. - Cell control mechanisms, such as tumor suppressor genes, regulate the cell cycle and prevent uncontrolled division. - Mutations that inactivate these controls can lead to cancer. - This statement is true because inactivation of cell control is a hallmark of cancer.Option 4: Mutations inhibit production of telomerase. - Telomerase is an enzyme that extends the telomeres of chromosomes, allowing cells to divide indefinitely. - In cancer cells, telomerase activity is often upregulated, not inhibited. - This statement is not true because mutations in cancer cells typically lead to increased, not decreased, telomerase production.Therefore, the statement that is not true for cancer cells in relation to mutations is:Option 4: Mutations inhibit production of telomerase.This corresponds to the correct option, which is Option 4.
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