To solve this problem, we need to identify the type of immune response responsible for the rejection of transplanted tissues or organs.$\newline$Let's analyze the options:$\newline \bullet$Option 1: Cell-mediated immune response$\newline$ - This type of immune response involves T cells, which play a crucial role in recognizing and attacking foreign tissues.$\newline$ - It is primarily responsible for the rejection of transplanted organs, as the T cells identify the transplanted tissue as foreign and initiate an immune response against it.$\newline \bullet$Option 2: Hormonal immune response$\newline$ - This is not a standard term used in immunology. The immune system does not typically involve a "hormonal" response in the context of tissue rejection.$\newline \bullet$Option 3: Physiological immune response$\newline$ - This is a vague term and does not specifically refer to any known immune mechanism responsible for organ rejection.$\newline \bullet$Option 4: Autoimmune response$\newline$ - An autoimmune response occurs when the immune system mistakenly attacks the body's own cells.$\newline$ - This is not the mechanism involved in transplant rejection, as the rejection is directed against foreign tissues, not the body's own cells.$\newline$Based on the analysis, the correct answer is Option 1: Cell-mediated immune response.$\newline$This corresponds to the correct option, which is Option 1.