Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
To solve this problem, we need to determine the percentage of progeny that will be diseased in a cross between two individuals heterozygous for the sickle cell anaemia gene.Let's denote the normal allele as and the sickle cell allele as Both parents are heterozygous, so their genotypes are We can set up a Punnett square to find the genotypes of the progeny:The possible gametes from each parent are and The Punnett square is as follows: - Parent 1 (top): - Parent 2 (side): - Resulting genotypes: - (normal) - (carrier, not diseased) - (carrier, not diseased) - (diseased)The genotypic ratio is:1 The percentage of progeny that are diseased () is:Therefore, the percentage of the progeny that will be diseased is 25%.This corresponds to Option 3.
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