To solve this problem, we need to identify the incorrect statement among the given options. Let's analyze each statement:$\newline \bullet$Option 1: Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms.$\newline$ - Glycolysis requires NAD$^+$ to accept electrons during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate.$\newline$ - This statement is correct.$\newline \bullet$Option 2: Glycolysis occurs in cytosol.$\newline$ - Glycolysis is a cytoplasmic process where glucose is broken down into pyruvate.$\newline$ - This statement is correct.$\newline \bullet$Option 3: Enzymes of TCA cycle are present in mitochondrial matrix.$\newline$ - The TCA cycle, also known as the Krebs cycle, occurs in the mitochondrial matrix.$\newline$ - This statement is correct.$\newline \bullet$Option 4: Oxidative phosphorylation takes place in outer mitochondrial membrane.$\newline$ - Oxidative phosphorylation occurs in the inner mitochondrial membrane, where the electron transport chain is located.$\newline$ - This statement is incorrect.$\newline$Therefore, the incorrect statement is Option 4.