To solve this problem, we need to determine the charge of DNA fragments. Let's analyze the properties of DNA:$\newline \bullet$DNA is composed of nucleotides, each containing a phosphate group.$\newline \bullet$The phosphate groups in DNA are negatively charged due to the presence of phosphate ions.$\newline \bullet$As a result, DNA fragments carry an overall negative charge.$\newline$Therefore, the correct answer is that DNA fragments are negatively charged.$\newline$This corresponds to Option 1: Negatively charged.