To solve this problem, we need to analyze each statement about lysosomes and determine which one is not correct.$\newline \bullet$Option 1: Lysosomes have numerous hydrolytic enzymes.$\newline$ - Lysosomes are known to contain a variety of hydrolytic enzymes that are capable of breaking down different types of biomolecules.$\newline$ - Therefore, this statement is correct.$\newline \bullet$Option 2: The hydrolytic enzymes of lysosomes are active under acidic pH.$\newline$ - The enzymes within lysosomes function optimally at an acidic pH, which is maintained inside the lysosome.$\newline$ - Therefore, this statement is correct.$\newline \bullet$Option 3: Lysosomes are membrane-bound structures.$\newline$ - Lysosomes are indeed membrane-bound organelles that contain digestive enzymes.$\newline$ - Therefore, this statement is correct.$\newline \bullet$Option 4: Lysosomes are formed by the process of packaging in the endoplasmic reticulum.$\newline$ - Lysosomes are actually formed by the Golgi apparatus, not the endoplasmic reticulum.$\newline$ - The enzymes are synthesized in the rough endoplasmic reticulum, but the packaging into lysosomes occurs in the Golgi apparatus.$\newline$ - Therefore, this statement is not correct.$\newline$Based on the analysis, the statement that is not correct is Option 4.