Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
Did you know?
Red blood cells have no nucleus, making more room to carry oxygen-binding haemoglobin.
To solve this problem, we need to understand the gene regulation mechanism of the lactose operon in coli, specifically involving the lac I gene product.The lactose operon is a classic example of an inducible operon, which is typically off but can be turned on in the presence of an inducer.The lac I gene encodes the repressor protein, which binds to the operator region of the operon and prevents transcription.In the absence of lactose, the repressor binds to the operator, blocking RNA polymerase from transcribing the structural genes.When lactose is present, it acts as an inducer by binding to the repressor protein, causing a conformational change that prevents the repressor from binding to the operator.This allows RNA polymerase to access the promoter and transcribe the genes necessary for lactose metabolism.Based on this understanding, the regulation is:Negative and inducible, because the repressor protein prevents transcription in the absence of lactose, and the presence of lactose induces transcription by inactivating the repressor.Therefore, the correct option is Option 2: Negative and inducible because repressor protein prevents transcription.
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